Evaluation of long read error correction software 长读纠错软件的评估

Evaluation of long read error correction software

Laurent Bouri∗ , Dominique Lavenier† Project-Team Genscale Research Report n° 9028 — february 2017 — 47 pages

Abstract:

This report compares several read error correction software that use 3rd generation sequencing technology (long reads). The experimentations have been performed on several reference genomes and the results evaluated with QUAST. The long read error correctors that have been evaluated are: LSC-2, Proovread, Ectools, Lordec, Nanocorr, Nas, Jabba, Pacbiotoca, Lorma et MHAP. The first 8 software can merge long and short reads, while the last 3 software use only long reads. Key-words: 3rd generation sequencing, long reads, correction

本报告比较了几种使用第三代测序技术(长读)的读错校正软件。

在几个参考基因组上进行了实验，并用QUAST对实验结果进行了评价。

被评估的长读错误校正器有:LSC-2、Proovread、Ectools、Lordec、Nanocorr、Nas、Jabba、Pacbiotoca、Lorma等。

前8个软件可以合并长读和短读，而后3个软件只使用长读。

关键词:第三代测序，长读，校正

参考

https://hal.inria.fr/hal-01463694/document

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