今天把开发环境一直到Windows7下，在IIS7.5中部署站点的时候遇到了这个问题，现在把我的解决方案贴出来。

错误信息：

Server Error in Application "DEMOSITE"
Internet Information Services 7.5

Error Summary
HTTP Error 500.23 - Internal Server Error
An ASP.NET setting has been detected that does not apply in Integrated managed pipeline mode.
Detailed Error Information
Module ConfigurationValidationModule
Notification BeginRequest
Handler PageHandlerFactory-Integrated
Error Code 0x80070032

Requested URL http://localhost:80/Default.aspx
Physical Path F:\Projects\*\Default.aspx
Logon Method Not yet determined
Logon User Not yet determined

Most likely causes:
This application defines configuration in the system.web/httpHandlers section.

Things you can try:
Migrate the configuration to the system.webServer/handlers section. You can do so manually or by using AppCmd from the command line - for example, %SystemRoot%\system32\inetsrv\appcmd migrate config "Default Web Site/". Using appcmd to migrate your application will enable it to work in Integrated mode, and continue to work in Classic mode and on previous versions of IIS.
If you are certain that it is OK to ignore this error, it can be disabled by setting system.webServer/validation@validateIntegratedModeConfiguration to false.
Alternatively, switch the application to a Classic mode application pool -
for example, appcmd set app "Default Web Site/" /applicationPool:"Classic .NET AppPool". Only do this if you are unable to migrate your application.
(Set "Default Web Site" and "Classic .NET AppPool" to your application path and application pool name)
Links and More InformationIntegrated mode is the preferred mode for running ASP.NET applications on IIS 7.0 and above.
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