(下图：进行多项选择的ListBox)

首先介绍一种简单地方法：就是通过自定义SystemColors类的参数来自定义WPF ListBox选择颜色的，SystemColors的HighlightBrushKey和HighlightTextBrushKey分别代表ListBoxItem被选中时文字和背景颜色，没有Highlight的BrushKey代表ListBox没有焦点时的选中项文字和背景颜色：

 1 <ListBox>2 3             <ListBox.Resources>4 5                 <Style TargetType="ListBoxItem">6 7                     <Style.Resources>8                                                     <!-- Background for Selected ListViewItem -->9                         <SolidColorBrush x:Key="{x:Static SystemColors.HighlightBrushKey}" Color="Pink"/>
10
11                         <SolidColorBrush x:Key="{x:Static SystemColors.ControlBrushKey}" Color="Gray"/>
12                           <!-- Foreground for Selected ListViewItem -->
13                         <SolidColorBrush x:Key="{x:Static SystemColors.HighlightTextBrushKey}" Color="Red"/>
14
15                         <SolidColorBrush x:Key="{x:Static SystemColors.ControlTextBrushKey}" Color="Green"/>
16
17                     </Style.Resources>
18
19                 </Style>
20
21             </ListBox.Resources>
22
23             <ListBoxItem>AAA</ListBoxItem>
24
25             <ListBoxItem>B</ListBoxItem>
26
27             <ListBoxItem>ccc</ListBoxItem>
28
29         </ListBox>这样的话，ListBox选中颜色变成了这样：

可是这种方法仅仅能改变统一的颜色，无法完成其他更多要求。

　　那么另一种更强大的方法就是在模板中定义。一种方法就是在控件模板中根据ListBoxItem的IsSelected属性判断是否被选中，然后利用WPF触发器来设置被选中后的样式。但是如果你的ListBox定义了数据模板的话你会发现数据模板是显示在控件模板之上的，因此控件模板上的某些显示元素会被数据模板盖住，如果此类情况发生，那么只能在数据模板上添加选中后的元素设置。这里可以通过一个RelativeBinding = FindAncestor的绑定来寻找可视化树中的ListBoxItem的IsSelected属性来在数据模板中判断ListBoxItem是否被选中。

<Window x:Class="WpfApplication1.Window1"xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"Title="Window1" Height="300" Width="300"><Window.Resources><Style TargetType="ListViewItem"><Style.Resources><SolidColorBrush x:Key="{x:Static SystemColors.ControlBrushKey}" Color="Yellow"/><SolidColorBrush x:Key="{x:Static SystemColors.HighlightBrushKey}" Color=" Red"/></Style.Resources><Setter Property="Panel.Background" Value="#00FFFFFF"/><Setter Property="Control.HorizontalContentAlignment"><Setter.Value><Binding Path="HorizontalContentAlignment" RelativeSource="{RelativeSource Mode=FindAncestor, AncestorType=ItemsControl, AncestorLevel=1}" /></Setter.Value></Setter><Setter Property="Control.VerticalContentAlignment"><Setter.Value><Binding Path="VerticalContentAlignment" RelativeSource="{RelativeSource Mode=FindAncestor, AncestorType=ItemsControl, AncestorLevel=1}" /></Setter.Value></Setter><Setter Property="Control.Padding" Value="2,0,0,0"/><Setter Property="Control.Template"><Setter.Value><ControlTemplate TargetType="ListViewItem"><Border BorderThickness="{TemplateBinding Border.BorderThickness}" Padding="{TemplateBinding Control.Padding}" BorderBrush="{TemplateBinding Border.BorderBrush}" Background="{TemplateBinding Panel.Background}" Name="Bd" SnapsToDevicePixels="True"><ContentPresenter Content="{TemplateBinding ContentControl.Content}" ContentTemplate="{TemplateBinding ContentControl.ContentTemplate}" ContentStringFormat="{TemplateBinding ContentControl.ContentStringFormat}" HorizontalAlignment="{TemplateBinding Control.HorizontalContentAlignment}" VerticalAlignment="{TemplateBinding Control.VerticalContentAlignment}" SnapsToDevicePixels="{TemplateBinding UIElement.SnapsToDevicePixels}" /></Border><ControlTemplate.Triggers><Trigger Property="Selector.IsSelected" Value="True"><Setter Property="Panel.Background" TargetName="Bd"><Setter.Value><DynamicResource ResourceKey="{x:Static SystemColors.HighlightBrushKey}" /></Setter.Value></Setter><Setter Property="TextElement.Foreground"><Setter.Value><DynamicResource ResourceKey="{x:Static SystemColors.HighlightTextBrushKey}" /></Setter.Value></Setter></Trigger><MultiTrigger><MultiTrigger.Conditions><Condition Property="Selector.IsSelected" Value="True"/><Condition Property="Selector.IsSelectionActive" Value="False"/></MultiTrigger.Conditions><Setter Property="Panel.Background" TargetName="Bd"><Setter.Value><DynamicResource ResourceKey="{x:Static SystemColors.ControlBrushKey}" /></Setter.Value></Setter><Setter Property="TextElement.Foreground"><Setter.Value><DynamicResource ResourceKey="{x:Static SystemColors.ControlTextBrushKey}" /></Setter.Value></Setter></MultiTrigger><Trigger Property="UIElement.IsEnabled" Value="False"><Setter Property="TextElement.Foreground"><Setter.Value><DynamicResource ResourceKey="{x:Static SystemColors.GrayTextBrushKey}" /></Setter.Value></Setter></Trigger><Trigger Property="UIElement.IsMouseOver" Value="True"><Setter Property="Panel.Background" TargetName="Bd" Value="Blue"></Setter></Trigger></ControlTemplate.Triggers></ControlTemplate></Setter.Value></Setter></Style></Window.Resources><Grid><ListView Margin="48,22,110,0" Name="listView1" Height="100" VerticalAlignment="Top"><ListView.View><GridView><GridViewColumn Header="12"/><GridViewColumn Header="12"/><GridViewColumn Header="12"/></GridView></ListView.View><ListViewItem>123</ListViewItem><ListViewItem>123</ListViewItem><ListViewItem>123</ListViewItem></ListView><TextBox Height="23" Margin="94,0,64,67" Name="textBox1" VerticalAlignment="Bottom" /></Grid>
</Window>