我的解决方法：

1. 修改根目录的php.ini为php5.ini
2. php5.ini中max_input_time改成300，同时在最后添加上 cgi.fix_pathinfo = 1
3. magento目录下.htaccess添加Options -MultiViews  （也就是去掉前面的井号）

php5.ini

register_globals = off
allow_url_fopen = offexpose_php = Off
max_input_time = 300  // 修改
variables_order = "EGPCS"
extension_dir = ./
upload_tmp_dir = /tmp
precision = 12
SMTP = relay-hosting.secureserver.net
url_rewriter.tags = "a=href,area=href,frame=src,input=src,form=,fieldset="; Only uncomment zend optimizer lines if your application requires Zend Optimizer support;[Zend]
;zend_optimizer.optimization_level=15
;zend_extension_manager.optimizer=/usr/local/Zend/lib/Optimizer-3.3.3
;zend_extension_manager.optimizer_ts=/usr/local/Zend/lib/Optimizer_TS-3.3.3
;zend_extension=/usr/local/Zend/lib/Optimizer-3.3.3/ZendExtensionManager.so
;zend_extension_ts=/usr/local/Zend/lib/Optimizer_TS-3.3.3/ZendExtensionManager_TS.so; -- Be very careful to not to disable a function which might be needed!
; -- Uncomment the following lines to increase the security of your PHP site.;disable_functions = "highlight_file,ini_alter,ini_restore,openlog,passthru,
;             phpinfo, exec, system, dl, fsockopen, set_time_limit,
;                     popen, proc_open, proc_nice,shell_exec,show_source,symlink"cgi.fix_pathinfo = 1  // 添加
memory_limit = 256M  // 添加
max_execution_time = 18000  // 添加magic_quotes_gpc = off  // 添加
flag session.auto_start = off  // 添加
zlib.output_compression = on  // 添加
suhosin.session.cryptua = off  // 添加
zend.ze1_compatibility_mode = off  // 添加
extension=mcrypt.so  // 添加

.htaccess

// ....Options -MultiViews //修改-删除全面的 #号// ...// 添加
RewriteEngine On
RewriteCond %{DOCUMENT_ROOT}%{REQUEST_URI} !-f
RewriteRule ^.+.php$ /bogusfileRewriteBase /

完全参考地址： http://www.magentocommerce.com/wiki/groups/227/error/no_input_file_specified

RewriteEngine On
RewriteCond %{DOCUMENT_ROOT}%{REQUEST_URI} !-f
RewriteRule ^.+.php$ /bogusfile

RewriteBase /yourbasepath/

cgi.fix_pathinfo = 1

Options -MultiViews

或者试试：

RewriteRule ^index.php/(.*)$ [L] 

源自：http://stackoverflow.com/a/19449172/4484798