于明明，男，博士，郑州大学化学与分子工程学院教授，硕士生导师，校级青年骨干教师。

中文名

于明明

职    业

教师毕业院校

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职    务

于明明人物经历

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1998年毕业于吉林大学。2005年5月于中科院理化所获博士学位。清华大学化学系博士后工作后，2007年到郑州大学工作。先后被评为校级青年骨干教师、省级青年骨干教师。[1]

于明明学术成果

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任职以来主持国家自然科学基金一项，参与一项，在Org. Lett.、Chem. Commun.、Inorg. Chem.、Langmuir、Anal. Chem.、J. Mater. Chem. C等杂志上发表论文四十余篇。2010年9月发表在Chem. Commun.的论文下载次数为当月该杂志的第三。2012年9月发表在New J. Chem.的文章为当月该杂志下载次数Top-Ten的第一。为Biosensors and Bioelectronics、Sensors and Actuators B、Analytica Chimica Acta、Dyes and Pigments等杂志的审稿人。[1]

于明明研究方向

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主要从事生物荧光分子探针和荧光高分子的研究。

生物荧光探针

研究具有高灵敏性、快速响应、高空间分辨率的荧光小分子、纳米复合物和生物高分子探针，探讨探针的识别机制，用于生物体内一些重要生理过程生命相关的荧光成像。

荧光功能高分子材料

研究高分子的荧光响应、能量传递、生物模拟以及高分子结构与荧光相互作用的规律。这方面研究期望用于荧光离子捕获、荧光染料以及生物标记与药物输运领域。[1]

于明明研究课题

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郑州大学化学与分子工程学院“青年学术骨干”教师基金

国家自然科学基金“具有双识别协同作用的锌、铜离子荧光分子探针”(项目批准号：50903075)

中国科学院光化学转换与功能材料重点实验室开放课题“人造捕光天线的分子设计与应用”

横向课题“新型显色离子吸附剂的研制”[1]

于明明代表文章

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1.Li, Z.X.;Liu, H.X.;Li, H.X.;Tsou, Y.H.; Gao, Y.L.; Xu*, X.Y.; Du, W.W.;Wei, L.H.;Yu, M.M.* Lysosome-targeting NIR Ratiometric Luminecent Upcoversion Nanoprobe toward Arginine. Sens. Actuators B,2019,280, 94–101.

2.Song, H.H.; Du, W.W.; Liu, C.X.; Li, Z.X.*; Zhang, H.Y.*; Wei, L.H.;Yu, M.M.*Self-Assembled Micellar Nanosensor toward pH with high photo-stability and its application in living cells. Sens. Actuators B,2018,273, 927–934.

3.Ban, Y.; Wang, R.H.; Li, Y.; An, Z.;Yu, M.M.*; Fang, C.J.*; Wei, L.; Li, Z.X. Mitochondria-targeted ratiometric fluorescent detection of hydrazine with fast response time. New J. Chem.,2018,42, 2030?2035.

4.Shi, B. J.;He,Y. Y.;Zhang, P. P.;Wang, Y. L.;Yu, M. M.*;Zhang, H. Y.*;Wei,L. H.;Li, Z. X.*Turn on fluorescent detection of hydrazine with a 1,8-naphthalimde derivative. Dyes Pigments,2017, 147, 152–159.

5.He,Y. Y.;Li, Z. X.*; Jia, Q. Y.;Shi, B. J.;Zhang, H. Y.*;Wei,L. H.;Yu, M. M.*Ratiometric fluorescent detection of acidic pH in lysosome with carbon nanodots. Chin. Chem. Lett.,2017,28(10), 1969-1974.

6.Li, H. X; Dong, H.;Yu, M. M.; Liu, C. X.;Li, Z. X.; Wei,L. H.;Sun, L. D.; Zhang, H. Y. NIR ratiometric luminescence detection of pH fluctuation in living cells with hemicyanine derivative-assembled upconversion nanophosphors. Anal. Chem.,2017,89, 8863?8869.

7.Shi, B. J.; Qi, S. J.;Yu, M. M.;Liu, C. X.;Li, Z. X.; Wei,L. H.;Ni, Z. H. Colorimetric and fluorescent detection of hydrazine with high sensitivity and excellent selectivity. Spectrochim. Acta A,2018,188, 208–212.

8.He,Y. Y.;Li, Z. X.;Shi, B. J.;An, Z.;Yu, M. M.;Wei,L. H.;Ni, Z. H.A new near-infrared ratiometric fluorescent probe for hydrazine. RSC Adv.,2017,7, 25634–25639.

9.Yu, M. M.*;Du, W. W.;Li, H. X.; Zhang, H. Y.*;Li, Z. X.* Near-infrared ratiometric fluorescent detection of arginine in lysosome with a new hemicyanine derivative. Biosens. Bioelectron.,2017,92, 385–389.

10.An, Z.;Li, Z. X.*;He, Y.; Shi, B.; Wei, L.;Yu, M. M.*Ratiometric luminescent detection of hydrazine with a carbon dots-hemicyanine nanohybrid system. RSC Adv.,2017,7, 10875–10880.

11.Li, Z. X.;*Zhang, W. Y.;Liu, C. X.;Yu, M. M.*;Zhang, H. Y.*;Guo,L.;Wei,L. H. A colorimetric and ratiometric fluorescent probe for hydrazine and its application in living cells with low dark toxicity. Sens. Actuators B,2017,241, 665–671.

12.Shi, B. J.; Gao, Y. L.;Liu, C. X.;Feng, W. Li, Z. X.;Wei,L. H.;Yu, M. M.*A ratiometric fluorescent sensor for pH fluctuation and its application in living cells with low dark toxicity. Dyes Pigments,2017,136, 522–528.

13.Li, Z. X.;Li, H. X.;Shi, C. X.;Yu, M. M.;Wei,L. H.;Ni Z. H. Nanomolar colorimetric quantitative detection of Fe3+and PPi with high selectivity. Spectrochim. Acta A,2016,159, 249–253.

14.Yu, M. M.*,Du, W. W.;Zhou, W.; Li, H. X.;Liu, C. X.;Wei,L. H.;Li, Z. X.*; Zhang, H. Y.A 1,8-naphthalimide-based chemosensor with an off-on fluorescence and lifetime imaging responsefor intracellular Cr3+and further for S2?. Dyes Pigments,2016,126, 279–285.

15.Li, Z. X.*; Li, H. X.; Shi, C. X.;Zhang, W. Y.;Zhou, W.;Wei,L. H.;Yu, M. M.* Naked-eye-based highly selective sensing of Fe3+and further for PPi withnano copolymer Film. Sens. Actuators B,2016,226, 127–134.

16.Yu, M. M.*;Xu, J.; Peng, C.; Li, Z. X.; Liu, C. X.; Wei,L. H. A novel colorimetric and fluorescent probe for detecting fluoride anions: from water and toothpaste samples. Tetrahedron,2016, 72, 273–278.

17.Xu, L. J.; Liang, X. Y.; Zhang, L.; Wu, J. B.;Li, Z. X.;Yu, M. M.*;Wei,L. H.* The vesicle formation ofβ-CD and AD self-assembly of dumbbell-shaped amphiphilic triblock copolymer. Colloid Polym. Sci.,2016, 294, 145–155.

18.Zhang, W. Y.; Liu, X. J.; Zhang, H. Y.; Feng, C. C.; Liu, C. X.;Yu, M. M.*;Wei,L. H.;Li, Z. X.* A fluorescent probe for benzenethiols and its application on test paper, in water samples and living cells. J. Mater. Chem. C,2015,3, 8248–8254.

19.Liu, C. X.; Shi, C. X.; Li, H. X.; Du, W. W.; Li, Z. X.*; Wei,L. H.;Yu, M. M.* Nanomolar fluorescent quantitative detection of formaldehyde with a 8-hydroxyquinoline derivative in aqueous solution and electrospun nanofibers. Sens. Actuators B,2015,219, 185–191.

20.Li, Z. X.*; Zhang, W. Y.;Liu, X. J.;Liu, C. X.;Yu,M. M.*;Wei, L. H.* Naked-eye-based selective detection of pyrophosphate with Zn2+complex in aqueous solution and electrospun nanofibers. RSC Adv.,2015,5, 25229–25235.

21.Liu, C. X.; Xu, J.; Yang, F.; Zhou, W.;Li, Z. X.*;Wei, L. H.;Yu,M. M.*Nanomolar Cu2+and F–naked-eye detection with a 1,8-naphthalimide-based colorimetric probe. Sens. Actuators B,2015,212, 364–370.

22.Du, W. W.; Xu, J.; Li, H. X.; Feng, C. C.;Yu,M. M.*;Li Z. X.;*Wei L. H. Naked-eye and fluorescent detection of basic pH and F?with a 1,8-naphthalimide-based multifunctional probe. RSC Adv.,2015,5, 15077–15083.

23.Zhou, W.; Dong, H.; Yan, H.; Shi, C. X.;Yu, M. M.*;Wei, L. H.;Li, Z. X.*HCHO-reactive molecule with dual-emission-enhancement property for quantitatively detecting HCHO in near 100% water solution. Sens. Actuators B,2015,209, 664–669.

24.Liu, X. J.; Zhang, W.Y.; Li, C. X.; Zhou, W.; Li, Z. X.*;Yu, M. M.*;Wei, L. H.Nanomolar detection of Hcy, GSH and Cys in aqueous solution, test paper and living cells. RSC Adv.,2015,5, 4941–4946.

25.Li, Z. X.*; Liu, X. J.; Zhao, W. Y.; Wang, S.; Zhou, W.; Wei, L. H.;Yu, M. M.* Naked-eye detection of C1–C4 alcohols based on ground-state intramolecular proton transfer. Anal. Chem.,2014,86, 2521?2525.

26.Su, Z.; Huang, S. S.; He, M.; Dong, C. F.; Wu, L. Z.; Li, C. H.; Liu, J. X.;Yu, M. M.*; Wei, L. H.* Synthesis and antibacterial performance of silver bromide and silver nanoparticles J. Nanoeng. and Nanomanuf.2014, 4(4), 330?335.

27.Liu, X. J.; Chen, M. X.; Liu, Z. P.;Yu, M. M.*; Wei, L. H.; Li, Z. X.* Synthesis of 1,8-naphthyridine and BF2-based isomers and their application in fluorogenic sensing Cd2+ Tetrahedron2014,70, 658?663.

28.Yu, M. M.*; Yuan, R. L.; Shi, C. X.; Zhou, W.; Wei, L. H.; Li, Z. X.*1,8-Naphthyridine and 8-hydroxyquinoline modified Rhodamine B derivatives: “Turn-on” fluorescent and colorimetric sensors for Al3+and Cu2+ Dyes Pigments2013,99, 887?894.

29.Li, X. Y.;Yu, M. M.; Liu, X. J.; Yang, F. L.;Wei, L. H.;Li, Z. X.*A dual-mode ratiometric and on?off fluorescent Al3+/Cu2+-chemosensor and the detection of F?/Al3+with ‘in situ’ prepared Al3+/Cu2+complex in aqueous solution. New J. Chem.2013,37, 2257-2260.

30.Li, H. Q.; Li, Z. X.*; Wu, L. Z.; Zhang, Y. N.;Yu, M. M.*;Wei, L. H.*Constructing metal nanoparticle multilayers with polyphenylene dendrimer/gold nanoparticlesvia “click” chemistry. Langmuir 2013,29, 3943?3949.

31.Li, Z. X.; Zhou, W.; Zhang, L. F.; Yuan, R. L.; Liu, X. J.; Wei, L. H.;Yu, M. M.*Highly selective ratiometric fluorescent detection of Fe3+with a polyphenyl Derivative. J. Lumin.2013,136, 141?144.

32.Li, Z. X.; Zhao, W. Y.; Li, X. Y.; Zhu, Y. Y.; Liu, C. M.; Wang, L. N.;Yu, M. M.*; Wei, L. H.; Tang, M. S.; Zhang, H. Y.* 1,8-Naphthyridine-derived Ni2+/Cu2+-selective fluorescent chemosensor with different charge transfer processses. Inorg. Chem.2012,51, 12444-12449.

33.Wang, L. N.,Yu, M. M.*, Liu, Z. T., Zhao, W. Y., Li, Z. X.,*Ni, Z. H., Li, C. C., Wei, L. H.*A visible light excitable “on-off” and “green-red” fluorescent chemodosimeter for Ni2+/Pb2+New J. Chem.2012,36, 2176–2179.

34.Li, Z. X.;Zhang, L. F.;Li, X. Y.;Guo, Y. K.; Ni, Z. H.; Chen, J. H.;Wei, L. H.;Yu, M. M.*A fluorescent color/intensity changedchemosensorfor Fe3+by photo-induced electron transfer (PET) inhibition of fluoranthene derivative. Dyes Pigm.2012,94, 60–65.

35.Huiqiang Li, Zhanxian Li, Linzhi Wu, Fang Liu, Jie Zhou, Miao Luan,Mingming Yu*, Liuhe Wei* Water-Soluble Starlike Poly(acrylic acid) Graft Polymer: Preparation and Application as Templates for Silver Nanoclusters Polym. Bull.,2012,68, 2229–2242.

36.Zhanxian Li, Wanying Zhao, Yuna Zhang, Lifeng Zhang,Mingming Yu*, Jinxia Liu* and Hongyan Zhang*An “off-on” fluorescent chemosensor of selectivity to Cr3+and its application to MCF-7 cells Tetrahedron,2011, 67, 7096–7100.

37.Zhan-Xian Li,Li-Feng Zhang, Wan-Ying Zhao, Xiao-Ya Li, Yong-Kai Guo,Ming-Ming Yu*, Jin-Xia Liu*Fluoranthene-based pyridine as fluorescent chemosensor for Fe3+ Inorg. Chem. Commun.,2011,14, 1656–1658.

38.Zhanxian Li, Lifeng Zhang, Lina Wang, Yongkai Guo, Lianheng Cai,Mingming Yu,* Liuhe Wei*Highly Sensitive and Selective Fluorescent Sensor for Zn2+/Cu2+and NewApproach for Sensing Cu2+by Central Metal Displacement Chem. Commun.,2011, 47, 5798–5800.

39.Zhanxian Li,Mingming Yu,* Lifeng Zhang, Ming Yu, Jinxia Liu, Liuhe Wei,* and Hongyan Zhang*A “switching on” fluorescent chemodosimeter of selectivity to Zn2+and its application to MCF-7 cells Chem. Commun.,2010, 46, 7169–7171.

40.Ming Ming Yu, Xia Li, Miao Luan, Jun Na Gao, Qiu Zhi Shi,Ming Sheng Tang, Liu He Wei An improved synthesis of bis(cyclopentadienone) Chin. Chem. Lett.,2010, 21, 1157–1161.

41.Ming-Ming Yu, Zhan-Xian Li, Liu-He Wei, Dong-Hui Wei, Ming-Sheng Tang A 1,8-Naphthyridine-based Fluorescent Chemodosimeter for the Rapid Detection of Zn2+and Cu2+ Org. Lett.2008, 22(10), 5115–5118.

42.Ming-Ming Yu, Hui-Zhong Kou, Zhong-Hai Ni, Chong-Chao Zhao, Ai-Li Cui Synthesis and Study of Ferromagnetic μ1,1-Azido-Bridged Manganese(II) Dinuclear Complexes with S=5 and S = 5 × 2 2 Ground State Eur. J. Inorg. Chem.2007, 5670–5676.[1]

于明明授权专利

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于明明、张文英、李占先、石彩霞、周婉、魏柳荷，一种高分子比色纳米薄膜材料及其制备方法以及用于Fe3+和焦磷酸根检测方面的应用。2015.05.26，中国，专利号：ZL201510292665.9

于明明、李海霞、严晗、周婉、李占先、魏柳荷，一种甲醛快速检测试剂及其制备方法与应用。2016.11.02，中国，专利号：ZL201410500026.2

于明明、张文英、刘兴江、周婉、李占先、魏柳荷，一种检测焦磷酸根的纳米纤维膜试条、制备方法及其应用。2015.11，中国，专利号：ZL201410402826.0

于明明、李占先、魏柳荷、刘兴江，一种氟硼荧光衍生物、其制备方法及应用。2015.11，中国，专利号：ZL201310171197.0

于明明、乔钰茜、李占先、魏柳荷、郭永开，2,4-二苯基-5,6-二吡啶基-苯酚及其制备。2015.6，中国，专利号：ZL201310518992.2

李占先、于明明、魏柳荷、刘兴江、赵万莹、周婉，一种低级醇检测探针、制备方法及应用。2015.4，中国，专利号：ZL201310198342.4

于明明、李占先、魏柳荷、张利锋、赵万莹、王丽娜，苯衍生物金属离子荧光探针及其应用。2014.4，中国，专利号：ZL201110169893.9

李占先、于明明、张利锋、虞明、魏柳荷、刘金霞，一种检测细胞内锌离子的分子荧光开关及其应用。2013.4，中国，专利号：ZL201010181802.9。

李占先、于明明、魏柳荷、张利锋、赵万莹、王丽娜，萘联苯衍生物金属离子荧光探针的制备及其识别检测生物样品或环境中Fe3+和/或Cu2+的应用。2013.4，中国，专利号：ZL201110169892.4。[1]

于明明公开专利

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于明明、施冰杰、刘春霞、李占先、魏柳荷，一种线粒体靶向的pH敏感的比率型荧光探针及其制备方法和应用。2016.07.06，中国，申请号：CN201610221971.8[1]

于明明荣誉称号

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2014年和2016年年终考核被评为优秀；

2011年发表教改论文一篇(物理化学实验教学的体会与思考)；

2016年发表教改论文一篇(高校全员育人的三级管理体系新探)；

2013、2014、2015和2016年化学学院高分子化学理论课网上教评均为优秀；

2013、2014和2015年药学院物理化学理论课网上教评优秀；

2013、2014和2016年物理化学实验课网上教评优秀；

2015年综合化学实验课网上教评优秀；

2013年和2014年两次被评为平安校园工作先进个人，2015年被评为工会工作积极分子；

先后担任2014级化学8班班主任和2016级化学1班班主任，作为2014级化学8班班主任2015年和2016年两次被评为郑州大学优秀班主任；[1]

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参考资料

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于明明

．郑州大学化学与分子工程学院[引用日期2019-08-23]