什么是癌症免疫治疗中的新靶标和肿瘤新抗原？

What are the emerging targets and neoantigens for immune therapy against cancer？

如何利用更具创新性的方法来开发针对以前未识别靶标的新疫苗?

How can we develop more innovative approaches to rational design of next-generation vaccines against previously unrecognized targets?

如何利用基于病原-宿主互作的新免疫策略，有效根除以耐药性为代表的慢性感染?

How can we develop novel host-directed immunotherapies to eradicate chronic infections, particularly those that are drug-resistant?

如何利用新技术与人工智能分析临床数据，助力免疫学科学发现能力？

How can we develop novel technological tools and AI to analyze clinical data to optimally facilitate scientific discovery in immunology?

如何通过B细胞与抗体功能的研究提升感染/肿瘤的治疗技术？

How can we better understand B-cell and antibody function to utilize and optimize technologies for treatment of infection and cancer?

慢性/潜伏性感染如何影响健康寿命？

How do chronic/latent infection and the microbiome affect healthy aging?

如何用创新的免疫学方法研制通用流感疫苗与艾滋病疫苗？

How can we use innovative immunology approaches to develop a universal flu vaccine and an AIDS vaccine?

如何通过对长效免疫记忆的研究对抗不同病原与肿瘤？

How can we research the immune system to understand the basis of long-term immune memory against diverse pathogens and tumors?

如何重建自身免疫病患者的免疫耐受?

How can we re-establish immune tolerance in autoimmune patients?

如何通过对免疫治疗耐受机制的更好认知，提高癌症患者的生存？

How can we better understand the resistance mechanisms to immunotherapies in order to improve cancer survival?

高福表示，12个重要科学问题是会议期间40余位专家基于自己的研究领域深入讨论和交流对众多免疫学科学问题的梳理与聚焦，从病原与宿主相互作用、肿瘤免疫特点、公共健康挑战三个方向共9场主题研讨中产生的27个覆盖不同免疫学问题的候选问题中凝练形成，最终由雁栖湖会议学术委员会讨论决定，并面向全球公开发布，以激励更多的青年科学家对新的问题发起挑战，进一步推进相关科学领域的发展和进步。